The islets of Langerhans, which are located in the pancreas gland, create the hormone insulin. This hormone is made up of a tiny protein. Insulin causes muscle cells and other body cells to accept glucose from the bloodstream, convert it to glycogen, a type of carbohydrate, and then store it. The body cells convert glycogen to glucose and use it as fuel when they need it. Insulin maintains a proper glucose level in the bloodstream in this way.
Insulin-producing cells are damaged in diabetes type I. As a result, less glucose is taken up from the bloodstream and used by the body cells, and glucose builds up in the blood.
THE CAUSES AND MECHANISMS OF TYPE I DIABETES
The exact cause of the condition is unknown. A possible cause is an auto-immune reaction that attacks the insulin-producing cells in the langerhansian islets. Another cause could be a virus infection. The sickness is also inherited to some extent.
The following physiological effects occur when glucose absorption into body cells is reduced and glucose instead accumulates in the blood:
-The body cells aren’t getting enough fuel to do the work they’re supposed to conduct.
-The blood’s molecular thickness (osmality) increases. Water is drained from the bodily tissues and into the bloodstream as a result of this. As a result, the tissues dry out and urine production rises.
-To obtain energy, the cells begin to break down protein and fat, resulting in weight loss and muscle loss.
SYMPTOMS OF DIABETES TYPE 1
-An increase in the amount of urine produced
-Hypertension (lack of water in the body)
-Excessive thirst as a result of increased urine production.
-A feeling of dryness in the mouth
-An abnormal high appetite
-Feeling exhausted and sluggish
-Loss of weight, even while eating well
-Impaired vision
If blood sugar levels do not return to normal, substances called ketones build up in the body, resulting in diabetic ketoacidosis. This life-threatening disorder can result in a coma and death.
DIABETES TYPE 1 TREATMENTS
Insulin injections are used to treat type 1 diabetes. Insulin-producing cells are implanted in the pancreas as an experimental treatment. Implanting stem cells in the pancreas that can grow into new insulin-producing cells is another investigational treatment.
Dr. Leelamohan P.V.R
MBBS. MD(GEN. MED) MHA Fellowship in Diabetology (UK) CCEDM (Indore)
Consultant Physician and Diabetologist
Padithem Health Care, 338, 27th Main, HSR Layout Sector-2, Opp. KLM Mall,Bangalore – 560 102.
Email: drleelamohan@gmail.com
TO BOOK AN APPOINTMENT : +91 9019888883
0 comments:
Post a Comment